This book integrates studies on the thought of Bernard de Mandeville and other philosophers and historians of Modern Thought. The chapters reflect a rethinking of Mandeville legacy and, together, present a comprehensive approach to Mandeville work. The book is published on the occasion of the 300 years that have passed since the publication of the Fable of the Bees. Bernard de Mandeville disassembled the dichotomies of traditional moral thinking to show that the outcomes of the social action emerge as new, non-intentional effects from the combination of moral opposites, vice and virtue, in such a form that they lose their moral significance. The work of this great writer, philosopher and physician is interwoven with an awareness of the paradoxical nature of modern society and the challenges that this recognition brings to an adequate perspective on the historical world of modernity.