The book discusses biofilms and adherent communities of microorganisms that play a significant role in livestock-associated infections. It explores the characteristics, formation, and consequences of biofilms in various livestock species and explains their involvement in diseases like mastitis, Johnes disease, caseous lymphadenitis, and more. It also explains intricate aspects of biofilm-related challenges, such as virulence, antibiotic resistance, quorum sensing, and inter-species communication. The book then explores the strategies for combatting biofilm-associated infections, encompassing phytomedicines, novel antimicrobials, and nanomedicines. This book serves as a great resource for researchers, veterinary practitioners and students by addressing these critical issues and providing a comprehensive understanding of biofilm dynamics in livestock infections, fostering improved diagnosis and treatment methodologies.