The “Challenges in Solid Tumors and Other Cancers: An Interdisciplinary Approach� is the twenty first volume of the “Interdisciplinary Cancer Research� series, publishes comprehensive volume on the challenges in cancer. The volume starts with a few chapters on solid tumors, including nano drug delivery for bone sarcomas, tumor-nerve interface, adoptive cell transfer, dendritic cell vaccines, CAR T cell Immunotherapy, immunogenic effect of modulated electro-hyperthermia, oncolytic viral therapies, apoptosis resistance, biopsy techniques, genetics, cytogenetics and liquid biopsy. The subsequent chapters explain different challenges on breast cancer, head and neck carcinomas, glioblastoma, hematologic cancers, lung cancers, cervical cancer, gastric cancer, hepatocellular carcinoma, and colorectal cancers. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on approach to challenges in cancer.