This book explores the idea of the ‘Entrepreneurial University’ within the institutional environment that focuses on the production, dissemination, and exploitation of knowledge. Keeping its gaze firmly on the constitutive elements of the knowledge-based institutional environment – the key actors and their interactions – the book makes important theoretical and empirical contributions to the burgeoning literature on academic entrepreneurship. The contributing chapters in the book draw insights from a range of disciplines including history, institutional and evolutionary economics, strategic management, entrepreneurship, and innovation studies to explore how institutions can create new business opportunities in turbulent times. This interdisciplinary approach has generated a rich and diverse set of insights on the idea of Entrepreneurial Universities for students, researchers, practitioners and policymakers interested in innovation and technology studies, entrepreneurship, and knowledge management.