This book is a curated compilation of works from the Global Conference on Entrepreneurship and Economy in an Era of Uncertainty 2025 (EEEU-25). The book explores the critical role of entrepreneurship in the digital age, emphasizing the necessity of innovation for businesses to navigate global crises such as pandemics, geopolitical tensions, and economic disruptions. It illuminates the transformative impact of digital innovation on fostering entrepreneurial ventures while underscoring the significance of adept organizational management in nurturing and sustaining successful businesses. The relationships between entrepreneurship, housing, and property markets in the global economy, and the implications of globalization on local real estate dynamics is also explored, investigating how macroeconomic factors such as interest rates, inflation, and foreign exchange rates influence entrepreneurial opportunities in the housing and property sectors, as well as their connection to broader economic trends. Covering topics such as the synergy between innovation and entrepreneurship, promoting sustainability in business practices, integrating supply chain and logistics management, and enhancing educational pursuits through entrepreneurial activities, this work provides valuable and practical insights for scholars and practitioners at the intersection of innovation, disruption, and entrepreneurship.