Perplexing ethical questions emerge when conducting research involving older adult participants. Fundamental ethical concerns often grappled with include the ability to obtain truly voluntary and competent informed consent, the proper role of surrogate decision making in the research context, and the equitable selection of research subjects. This volume brings to the forefront a discussion of how to encourage essential research specifically designed to benefit older persons while protecting the legal and ethical rights of actual and potential older research participants. Highly qualified and diverse contributors analyze and explain some of the most salient and legal conundrums implicated in the design, conduct, interpretation, and application of research protocols that touch on these problems of aging and the aged.