This book presents 101 unique and extraordinary cases in interventional radiology (IR) and endovascular therapy. Extreme IR is an internationally recognized event that Dr. Ziv Haskal created and held in early 2000s at mountaintop venues, then at successive Society of Interventional Radiology annual conference meetings, and later, published monthly within the Journal of Vascular and Interventional Radiology (JVIR) for which he was editor-in-chief for 10 years. The ever-popular Extreme IR sessions at conferences have drawn more than 5,000 attendees. Cases are presented in a rapid-fire format designed to maximize relevancy, excitement, and unique knowledge. This book aims to replicate that experience for a wider audience. The book is divided into twelve sections, including venous, portal hypertension, and biliary, arterial, oncology, etc. cases. Most cases span two pages and include large, illustrative images with bullet-pointed text to present essential information in a concise and focused fashion. The global list of authors exemplifies the extraordinary breadth of the cases for interventional radiologists, endovascular specialists. It is ideal for interventional radiologists and endovascular specialists at all levels of seniority and training.