Fractional calculus and its applications are fascinating research areas in many engineering disciplines. This book is a comprehensive collection of research from the authors group, which is one of the most active in the fractional calculus community worldwide and is the birthplace of one of the four MATLAB toolboxes in fractional calculus, the FOTF Toolbox. The book presents high-precision solution algorithms for a variety of fractional-order differential equations, including nonlinear, delay, and boundary value equations. Currently, there are no other universal solvers available for the latter two types of equations. Through this book, readers can systematically study the mathematics and solution methods in the field of fractional calculus and apply these concepts to different engineering fields, particularly control systems engineering. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.