GABA and Sleep - E-book - 9783034602266

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Gaba And Sleep - ENG

Molecular, Functional And Clinical Aspects

Jaime M. Monti; Seithikurippu Ratnas PandiPerumal; Hanns Möhler

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Sinopsis

ISBN:	9783034602266
Formato:	ePub
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Ciencia
Subtema:	Ciencias de la Vida anatomía humana y fisiología
Año de publicación:	2010-09-28

GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia. The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events. Â

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