This handbook examines digital systemic psychotherapy and counseling for individuals, couples, families, and groups. It addresses online supervision for professionals working in mental health services as well as online training in systemic family and couple therapy. The handbook explores the dramatic changes in the use of digital technology since the COVID-19 pandemic. It provides a theoretical perspective on the impact of digital technology on family life as well as therapeutic work. The volume offers state-of-the-art practical recommendations to trainees, therapists, supervisors, and trainers for implementing online systemic practices. Key areas of coverage include: Therapeutic alliance in online systemic therapy. Online systemic therapy with individuals presenting psychological difficulties as well as families of adolescents with mental health issues. Online couples therapy. Online systemic group therapy with oncology patients. Online multifamily group therapy with youths facing psychotic symptoms. Online systemic supervision with individuals and teams. Online training in systemic couple and family therapy. Methods and guidelines for online systemic practices. The Handbook of Online Systemic Therapy, Supervision, and Training is a must-have resource for researchers, professors, and graduate students as well as clinicians, therapists, and other professionals in clinical psychology, family studies, psychotherapy, social work, public health, and all interrelated disciplines.