This book constitutes revised selected papers from two VLDB workshops: The International Workshop on Polystore Systems for Heterogeneous Data in Multiple Databases with Privacy and Security Assurances, Poly 2021, and the 7th International Workshop on Data Management and Analytics for Medicine and Healthcare, DMAH 2021, which were held virtually on August 2021.  For Poly 2021, 7 full and 2 short papers were accepted from 10 submissions; and for DMAH 2021, 4 full papers together with 2 invited papers were accepted from a total of 7 submissions. The papers were organized in topical sections as follows: distributed information systems in enterprises, enterprise access to data constructed from a variety of programming models, data management, data integration, data curation, privacy, and security innovative data management and analytics technologies highlighting end-to-end applications, systems, and methods to address problems in healthcare.