This book focuses on challenges that have arisen because of trash discharges and their potential causes and provides long-term sustainable solutions. Globally, the COVID-19 pandemic has caused immense devastation, leading to numerous fatalities as well as substantial economic losses and health issues. With the rise in COVID-19 cases, the amount of biomedical waste has multiplied, exposing more people to the epidemic. For developing countries, waste management is already a problem, and the waste generated during this pandemic situation has made things worse. If improper waste management techniques are not changed, the world will face a new crisis that could be referred to as a "garbage crisis." The increased quantity of COVID-19-associated waste (CAW) and their presence in the environment make them more vulnerable, potentially increasing the danger of food chain contamination. A few countries have already started putting emergency plans in place to address the “waste crisis.� Given the paucity of information on the mutational features and potential hosts of this newly discovered COVID-19, there is a pressing need for an effective plan to protect Indias ecosystem against further contamination. To handle the current crisis and prevent the anticipated waste disaster, it is imperative to construct a more effective, automated, computerized, and well-modified waste management system during the COVID-19 period.