This book constitutes the refereed post-conference proceedings of the 6th EAI International Conference on Innovations and Interdisciplinary Solutions for Underserved Areas, InterSol 2023, held in Flic en Flac, Mauritius, in September 16-17, 2023. The 25 papers presented were selected from 73 submissions and issue different problems in underserved and unserved areas. They face problems in almost all sectors such as energy, water, communication, climate change, food, education, transportation, social development, and economic growth. The papers are clustered in tracks as follows: Intelligent Systems and Security; Blockchain and Machine Learning Algorithms; Sustainable Technologies and Environmental Impact; Digital Learning and Social Adoption; Networking Technology for Social Impact.