Iron Acquisition by the Genus Mycob - E-book

eBook

Iron Acquisition By The Genus Mycobacterium - ENG

History, Mechanisms, Role Of Siderocalin, Anti-tuberculosis Drug Development

eBook

$1,100.00

Disponible

Información adicional
Sinopsis

ISBN:	9783319003030
Formato:	ePub
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Ciencia
Subtema:	Ciencias de la Vida microbiología
Año de publicación:	2013-05-17

Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. Â The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed.Â The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.

eBooks