This book analyzes the role of language in scientific research and develops the semantics of science from different angles. The philosophical investigation of the volume is divided into four parts, which covers both basic science and applied science: I) The Problem of Reference and Potentialities of the Language in Science; II) Language and Change in Scientific Research: Evolution and Historicity; III) Scientific Language in the Context of Truth and Fiction; and IV) Language in Mathematics and in Empirical Sciences. Language plays a key role in science: our access to the theoretical, practical or evaluative dimensions of scientific activity begins with the mastery of language, continues with a deepening in the use of language and reaches the level of contribution when it creates new terms or changes them in sense and reference. This reveals the compatibility between objectivity in semantic contents and historicity in the progress of science. This volume is a valuable enrichment to students, academics and other professionals interested in science in all its forms, who seek to deepen the role that language plays in its structure and dynamics.