This book brings into dialogue approaches from anthropology, sociology, visual art, theatre, and literature to question what kinds of relations, frames and politics constitute pain across disciplines and methodologies. Each chapter offers a unique window onto the notoriously difficult problem of how pain is defined and communicated. The contributors reimagine the value of images and photography, poetry, history, drama, stories and interviews, not as ‘better’ representations of the pain experience, but as devices to navigate the complexity of pain across different physical, social, and intersubjective domains.  This innovative collection provides a new access point to the phenomenon of pain and the materialities, affects, structures and institutions that constitute it. This book will appeal to readers seeking to better understand pain complexity and the social and affective ecologies through which pain is known, communicated and lived.