This book offers a detailed and scholarly historical and philosophical examination of French scepticism from Descartes to the beginning of the Enlightenment by examining the views of Pierre-Daniel Huet (1630–1721). It shows the crucial role played by Huet in the modification of the early modern sceptical tradition: from a practical perspective closer to ancient scepticism, mostly presented by Montaigne and Charron, to an epistemological and metaphysical perspective strongly influenced by Descartes doubt. The book examines and gives original interpretations of the various sceptical (and semi-sceptical) views held in the period and their connections to Huet own scepticism. Besides known philosophers such as Descartes, Gassendi, Pascal and Bayle, the book also accesses sceptical views held by secondary figures such as La Mothe Le Vayer and Simon Foucher and others who have not thus far been connected to the sceptical tradition such as Jean-Baptiste du Hamel and Madeleine de Scudéry. The book is useful for scholars in the field of early modern ideas: philosophical, religious and scientific.