A key reference for reliability professionals worldwide and widely adopted as a textbook by universities across many countries. This material also aligns with the Certified Reliability Engineer (CRE) curriculum set by the American Society for Quality (ASQ), making it a valuable resource for those preparing for the CRE certification. With a strong focus on practical engineering applications, the Sixth Edition of Practical Reliability Engineering continues to offer a balanced blend of reliability theory and real-world applications. This edition has been comprehensively updated to reflect the latest advancements in industry practices and state-of-the-art reliability engineering. Each chapter includes practical examples, and course instructors have access to a Solutions Manual and PowerPoint slides for training support available from the author at [email protected]. The sixth edition introduces several significant updates. Every chapter has been refreshed with new material, and two new chapters — Repairable Systems and Human Reliability — have been added. This edition also covers emerging topics in reliability engineering, such as prognostics and health management (PHM), Agile hardware development, the reliability challenges posed by the ongoing miniaturization of integrated circuits, and many more, ensuring that the content remains relevant to modern technological developments. Written by two highly qualified reliability professionals, each with decades of experience, this book covers nearly every aspect of reliability science and practice, making it a comprehensive reference guide. Practical Reliability Engineering has, over the years, helped to train multiple generations of reliability engineers and continues to be an essential resource for both emerging professionals and seasoned experts alike.