This volume highlights the latest advances, innovations, and applications in bituminous materials and structures and asphalt pavement technology, as presented by leading international researchers and engineers at the RILEM International Symposium on Bituminous Materials (ISBM), held in Lyon, France on December 14-16, 2020. The symposium represents a joint effort of three RILEM Technical Committees from Cluster F: 264-RAP “Asphalt Pavement Recycling�, 272-PIM “Phase and Interphase Behaviour of Bituminous Materials�, and 278-CHA “Crack-Healing of Asphalt Pavement Materials�. It covers a diverse range of topics concerning bituminous materials (bitumen, mastics, mixtures) and road, railway and airport pavement structures, including: recycling, phase and interphase behaviour, cracking and healing, modification and innovative materials, durability and environmental aspects, testing and modelling, multi-scale properties, surface characteristics, structure performance, modelling and design, non-destructive testing, back-analysis, and Life Cycle Assessment. The contributions, which were selected by means of a rigorous international peer-review process, present a wealth of exciting ideas that will open novel research directions and foster new multidisciplinary collaborations.