The book provides an in-depth exploration of the relationship between psychopathology and neuroscientific foundations, focusing on how neuroscience explains changes in consciousness. It examines what happens in the brain during states such as anxiety, addressing symptoms like lack of motivation or feelings of depression that many people experience at some point. Psychiatric disorders are complex psychopathological phenomena that require detailed observation and assessment. This comprehensive resource systematically describes all symptoms, enriched with case studies that deepen both observation and clinical experience. Each chapter includes definitions, clinical perspectives, and diagnostic approaches, with neuroscientific models illustrated for each symptom group and specific aspects. Targeted at psychiatrists, other professionals in psychosocial care, and interested students, the book aids practitioners in providing clear and accurate explanations of symptoms to patients. The new edition has been thoroughly revised and updated, incorporating the latest research findings on contemporary topics, such as hallucinations and deep learning.