This Festschrift celebrates Teddy Seidenfeld and his seminal contributions to philosophy, statistics, probability, game theory and related areas. The 13 contributions in this volume, written by leading researchers in these fields, are supplemented by an interview with Teddy Seidenfeld that offers an abbreviated intellectual autobiography, touching on topics of timeless interest concerning truth and uncertainty. Indeed, as the eminent philosopher Isaac Levi writes in this volume: In a world dominated by Alternative Facts and Fake News, it is hard to believe that many of us have spent our life work, as has Teddy Seidenfeld, in discussing truth and uncertainty. The reader is invited to share this celebration of Teddy Seidenfeld work uncovering truths about uncertainty and the penetrating insights they offer to our common pursuit of truth in the face of uncertainty.