This book addresses key challenges and advancements in an increasingly automated transport sector, focusing on aeronautical information management and the evolving role of air traffic controllers in ensuring safe, secure, and sustainable aviation. It examines transport safety and security in highly automated environments, including the integration of smart power systems, renewable energy, artificial intelligence, and cybersecurity. Special attention is given to force health protection and human?system integration, including the flight surgeon?s perspective on sustaining operational performance. The book covers spatial disorientation, infrastructure resilience, hybrid electric propulsion, unmanned operations, robotic systems, and AI-related cybersecurity risks, highlighting the strategic links between transport safety, data protection, harmonized safety education, and operational resilience across allied regions.