This book examines the development of an information technology architecture that promotes automated, agile, and transformative enterprises while adhering to environmental and ethical guidelines. It explores how digital transformation, combined with dynamic business aspects?such as fluctuating workloads, agile responses to customer demands, and economic and ecological sustainability?requires strategic foresight and careful management. The book also examines the IT infrastructure transformation essential for promoting agile enterprises, including the mental alignment of personnel and organizational structures, from the first steps, to continuous adaptation to a rapidly evolving market and changing technology landscape. In addition, it outlines how an AI-driven methodological approach can be used to monitor the significant consumption of economic and human resources and enable early optimization measures consistent with agility and rapidly changing business objectives. This book is a valuable resource for executives and offers essential insights into shaping the digital transformation toward agile enterprises.