This book is a vital resource for understanding apheresis therapy, a crucial intervention in intensive care settings for managing severe medical conditions. Apheresis modalities have significantly influenced medical practices worldwide. This second edition, serves as a compact and practical manual for healthcare professionals, offering critical insights into the application of apheresis in emergency situations. The chapters cover a wide range of topics, including the basic theory of apheresis, methods for removing pathogenic substances, and various plasma exchange therapies. Expert contributors investigate the selection of blood purification devices, treatment volume determination, and vascular access, while also addressing potential complications such as hypotension, bleeding, and infections. The book also explores the indications and target diseases for apheresis, including autoimmune-related diseases, cardiac conditions, and inflammatory bowel disease. This indispensable resource is designed for medical students, critical care professionals, and sales representatives involved with apheresis products. It provides a thorough understanding of the latest advancements in apheresis therapy, making it a must-have for anyone in the field. Whether youre a researcher, practitioner, or educator, this book offers valuable knowledge to enhance your expertise in apheresis therapy.