This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues – such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control – on one hand, and the diagnostic yield and clinical meaning on the other. The volume offers several case studies – including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors– that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.