This unique book addresses the need for the scholarly works that include the voices of clinicians, community stakeholders, and leaders of faith-based institutions in various phases of developing, implementing, and evaluating programs that address health inequities and health disparities among marginalized, middle and low resource communities. Another feature of this book is the contributions to the evidence on SDOH from not only academic researchers but clinicians, community partners, and leaders of faith-based institutions. The overall purpose of this book is really to highlight global community-based programs that have been implemented in marginalized, middle and low resource global communities. The communities represented are rural, urban-inner city, located in Southern, Northeastern, and Western U. S. as well as global communities from Malawi, Kenya, Tanzania, Ethiopia, Botswana, the Grenadines, Nigeria, and Peru. For ease of reading, the editors have further classified these SDOH conditions illustrated in chapters organized according to a 4 pillar SDOH framework of social, cultural, physical environment, social environment, and policy conditions. This book contributes to a diverse perspective of the possibilities of incorporating SDOH into communities and faith-based institutions. The long-range objectives are to inform, inspire, and encourage the novice and senior faculty, clinician, community stakeholder, and faith-based institutional leader to develop, implement, and evaluate SDOH on health and health disparities among the communities they serve. The intended audience of this book is faculty of nursing, public health, and medicine in academic and practice settings; professional leaders of nursing, public health, and medicine; community stakeholders, and leaders of faith-based institutions engaged in partnerships with health care providers. This text might also be useful to faculty of foreign studies, and behavioral sciences.