This volume examines recent progress in the development of rational strategies for tissue regeneration, including approaches for wound healing and the management of chronic wounds. These advances build on the understanding that tissue repair is an energy-dependent process and on the identification of molecules that help overcome energy deficits during healing. The book also discusses the design of controlled drug delivery systems and the development of composite materials for tissue regeneration and wound repair, based on synthetic or biological polymers and nanoparticles, which offer improved performance compared to conventional materials. Contributions from leading researchers provide an overview of key developments and current directions in this evolving area of biomedical research.