This volume is dedicated to the life and work of Ernest Nagel (1901-1985) counted among the influential twentieth-century philosophers of science. Forgotten by the history of philosophy of science community in recent years, this volume introduces Nagel philosophy to a new generation of readers and highlights the merits and originality of his works. Best known in the history of philosophy as a major American representative of logical empiricism with some pragmatist and naturalist leanings, Nagel interests and activities went beyond these limits. His career was marked with a strong and determined intention of harmonizing the European scientific worldview of logical empiricism and American naturalism/pragmatism. His most famous and systematic treatise on, The Structure of Science, appeared just one year before Thomas Kuhn even more renowned, The Structure of Scientific Revolutions. As a reflection of Nagel interdisciplinary work, the contributing authors’ articles are connected both historically and systematically. The volume will appeal to students mainly at the graduate level and academic scholars. Since the volume treats historical, philosophical, physical, social and general scientific questions, it will be of interest to historians and philosophers of science, epistemologists, social scientists, and anyone interested in the history of analytic philosophy and twentieth-century intellectual history.