This book reports on innovative concepts and practical solutions at the intersection between engineering design, production and industrial management. It covers cutting-edge design, modeling and control of dynamic and multiphysics systems, knowledge management systems in industry 4.0, cyber-physical production systems, additive and sustainable manufacturing and many other related topics. It also highlights important collaborative works between different countries and between industry and universities. Gathering the proceedings of the 12th International Conference on Integrated Design and Production, CPI 2022, held on May 10-12, 2022, at École Nationale Supérieure dArts et Métiers (ENSAM), in Rabat, Morocco, this book gathers carefully peer-reviewed chapters, with extensive information for researchers and professionals in the broad area of engineering design,  production and management.