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| ISBN: | 9780470515532 |
|---|---|
| Formato: | Page Fidelity |
| Idioma: | Inglés |
| Editorial: | Wiley Global Research (STMS) |
| Tema: | Ciencia |
| Subtema: | Ciencias de la Vida biología molecular |
| Año de publicación: | 2008-04-30 |
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, partial T cell activation, and the role of apoptosis in tolerance. Careful consideration is also given to the clinical applications of our understanding of immunological tolerance, with specific chapters dealing with T cell activation during tumour therapy, antiantigen specific immune suppression, tolerance in infectious diseases, tolerance during pregnancy, and tolerance during various autoimmune diseases.